Marijuana May Help Prevent Erection Issues in High-Risk Individuals

Keith G. Tolman
Written by: Keith G. Tolman
Published 07/22/2015
Updated: 07/22/2015

Studies have shown that men with high cholesterol are at increased risk for sexual health problems such as erectile dysfunction. Too much cholesterol can clog blood vessels and decrease blood flow to the penis. This effect may inhibit a man’s ability to get an erection. If left untreated, high cholesterol can lead to permanent erection problems.

High cholesterol is one of the most significant risk factors for erectile dysfunction. Doctors believe that this is primarily due to damaged blood vessels in the penis. Leaking blood vessels make it difficult for the penis to become fully engorged. Oxidative stress due to high cholesterol can also have a negative impact on overall blood circulation.

Fortunately, there’s hope for this at-risk population of men. A new study published in Clinical and Developmental Immunology suggests that marijuana may help prevent erectile dysfunction in men with high cholesterol. The cannabinoids in marijuana may counteract blood vessel damage brought on by high cholesterol. Marijuana may help relax the tissues in the penis and enable them to function normally. Cannabinoids may also reduce oxidative stress, which is another major cause of erectile dysfunction.

During the study, the researchers targeted certain pathways, called CB2 receptors, which are related to marijuana. These receptors are located in many parts of the body, including the penis. By activating these receptors, the researchers were able to reduce blood vessel damage in mice with high cholesterol.

After 21 days of regular treatment, tissue samples taken from the mice showed less damage. Overall, the researchers found fewer cholesterol-related injuries and abnormal tissue when compared to the control group. Overall, the researchers found that CB2 activation appeared to decrease factors that may contribute to erectile dysfunction.

The research in this area of sexual health is still in the early stage. However, the initial results may be quite promising for men with erectile dysfunction due to high cholesterol. This research sheds some light on the ongoing conversation about marijuana and sexual health. Until recently, sexual health studies have mostly focused on the short-term effects of marijuana.

Many previous studies have provided conflicting results. Some research conducted in humans suggested that marijuana might increase sexual desire in men. Other studies found that certain marijuana pathways may interfere with a man’s ability to get and maintain a firm erection for sexual activity. For example, a 2011 study found that marijuana could have an antagonizing effect on certain receptors in the penis, which can lead to erectile dysfunction.

The new findings indicate that marijuana might offer long-term benefits to men with high cholesterol. These results have important implications that could lead to marijuana being used to treat erectile dysfunction. It’s estimated that more than 30 million American men suffer from this sexual health problem. America seems to be moving towards the legalization of medical marijuana. Given the success of Viagra, there’s a possibility that these results could accelerate that process. However, the researchers state that more studies need to be conducted to confirm the results.

Keith G. Tolman

Keith G. Tolman

Dr. Tolman is Professor of Medicine and Pharmacology at the University of Utah in Salt Lake City. He received his medical degree from the University of British Columbia in Vancouver, Canada followed by a residency at Baylor Medical University in Houston and GI Fellowship at the University of Utah.
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